There are a few comic strips that have a recurring baseball storyline or some regular baseball references. Peanuts comes to mind. Baseball Dad posted a few panels of Steve Moore's In the Bleachers. You can find many others here.
The two that I stumbled across are The Heart of Juliet Jones and Steve Canyon. Soap opera-y strips. These came from May 19, 1958. (click on the panel for a larger image).
No, I didn't search out panels from the following days. I don't know what happens. Don't ask.
Images snagged from the Plattsburgh Press-Republican.